FORCE Blog

This blog will cover topics of interest that affect our community. Unless otherwise stated, the blog articles will be written by Sue Friedman, Executive Director of FORCE.

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Posts Tagged ‘metastatic breast cancer’

October 29, 2018

PARP Inhibitors Take Center Stage

by Piri Welcsh, PhD “PARP inhibitor therapy, I think it’s fair to say, very likely would not be part of our armamentarium now had it not been for FORCE.” These were the words of Mary-Claire King, PhD as she accepted her 2018 FORCE Spirit of Empowerment award.  “Armamentarium,” I confess, was a word I had … + read more

April 12, 2018

PARP Inhibitors and Hereditary Cancer: What’s New?

by Sue Friedman PARP inhibitors are drugs designed specifically to treat cancers in people with certain inherited mutations, including BRCA1 and BRCA2, among others. These drugs block an enzyme – known as PARP – used by cells to repair damage to their DNA. Although these agents seem to be most effective in people with mutations—not just … + read more

February 22, 2018

FORCE Participates in The Metastatic Breast Cancer Alliance

by Diane Rose There are large gaps in research, support, information, advocacy and resources for people with advanced breast cancer. People with metastatic breast cancer who also have an inherited mutation like BRCA or PALB2 face additional challenges associated with children and other relatives sharing the same hereditary cancer risk. The Metastatic Breast Cancer Alliance … + read more

May 10, 2016

Experience with Oncology Clinical Trial Participation and Impact on Future Trial Design and Conduct

Note: Last year, TESARO, a pharmaceutical company developing a new PARP inhibitor for treatment of ovarian cancer and metastatic breast cancer, asked FORCE to help recruit previous clinical trial participants to join focus groups across the U.S. TESARO wanted to understand the patient experience to build clinical trials that are more responsive to patient needs. We … + read more

Connect with others.

Call our Helpline

Our helpline offers peer support for people concerned about hereditary cancer. All calls are confidential. Call any time.

Join a Local Group

FORCE has outreach groups throughout the United States and in Essex, United Kingdom that meet periodically to offer peer support, and share resources.

FORCE:Facing Our Risk of Cancer Empowered