FORCE Blog

This blog will cover topics of interest that affect our community. Unless otherwise stated, the blog articles will be written by Sue Friedman, Executive Director of FORCE.

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Posts Tagged ‘BRCA2’

November 17, 2016

Results from the KNOW MORE Ovarian Cancer Survey: Your Comments

by Sue Friedman FORCE’s KNOW MORE campaign helps women diagnosed with ovarian, fallopian tube, or primary peritoneal cancers make informed decisions about genetic counseling and testing for inherited gene mutations. We launched a survey, which was completed by over 1,600 women with ovarian cancer. This blog continues our series on the survey results. We received over … + read more

November 14, 2016

Voices of FORCE: A BRCA Mutation is a Factor in Pancreatic Cancer

By Rona Greenberg Hereditary breast and ovarian cancer is part of my family history. My grandmother, Rebecca, for whom I am named, died from breast/ovarian cancer in1934; my mother was ten years old. My mother died from the same cancer in 1967; I was nineteen years old with three younger sisters. In 1997, I was … + read more

November 1, 2016

Learn About Hereditary Pancreatic Cancer

by Lisa Rezende, PhD November is Pancreatic Cancer Awareness Month. FORCE wants to raise awareness of the risk of pancreatic cancer in the hereditary cancer community. Pancreatic cancer is rare but BRCA carriers have a high risk, up to 5% compared to the 1.5% for the general population. Between BRCA carriers, the risk is higher … + read more

October 25, 2016

Guest Blog: Genetic Variants of Uncertain Significance

by Nancy Ledbetter Early on in my genetics nursing career, I remember explaining the possibility of a variant of uncertain significance (VUS) to a patient, who laughed and said, “Variant of uncertain significance? That sounds like something out of Monty Python!” I had to admit she had a good point. It sounds like a ridiculous … + read more

September 30, 2016

HBOC Week Special: Inherited Mutations in BRCA1/2 and Related Genes More Common Than Expected in Men with Advanced Prostate Cancer

Guest blog by Heather H. Cheng, MD, PhD Researchers have long been aware that prostate cancer carries a substantial familial risk. New data (Robinson, et al Cell 2015) from the Stand Up To Cancer-Prostate Cancer Foundation International Dream Team collaborative group examined the genetic sequence of 150 tumors from men with advanced, hormone-resistant, metastatic prostate … + read more

September 6, 2016

Ovarian Cancer Survivor Survey Results: Education is Key to Informed Decision-making

FORCE’s KNOW MORE campaign helps women diagnosed with ovarian, fallopian tube, or primary peritoneal cancer make informed decisions about genetic counseling and testing for inherited mutations. To better understand their information needs, we launched a survey for women with ovarian cancer. Over 1,600 women completed our survey. This blog continues our series on survey results. How … + read more

July 28, 2016

Metastatic Hereditary Breast Cancer Treatment Research: BROCADE 3 Study

By Heather Han, MD and Sue Friedman Metastatic Hereditary Breast Cancer Research There are major gaps in research, resources, and support for people with metastatic breast cancer – cancer that has spread beyond the breast and lymph nodes. A promising area of research is focusing on new treatments for hereditary metastatic breast cancer caused by … + read more

July 5, 2016

Cancer Screening Guideline Loopholes and Confusion Jeopardize Coverage of Services: Part II of Access to Care Series

by Lisa Schlager Over 2 million women in the U.S. are at high risk for breast cancer due to family history. Additionally, nearly a million Americans carry an inherited BRCA mutation and a number of other genetic mutations have also been linked to increased risk of breast, ovarian and other cancers. Several organizations develop cancer … + read more

June 17, 2016

National Task Force Guideline Gaps Hinder Access to Genetic Testing

by Lisa Schlager Nearly a million Americans carry an inherited BRCA mutation associated with hereditary breast, ovarian cancer, and related cancers (HBOC) and it is estimated that 2.3 million women in the U.S. are at high risk for breast cancer due to family history. A number of other genetic mutations have also been linked to … + read more

June 2, 2016

Results from the KNOW MORE Survey: Genetic Counseling and Testing in Women with Different Types of Ovarian Cancer

KNOW MORE is a campaign designed by FORCE to help women diagnosed with ovarian, fallopian tube, or primary peritoneal cancers make informed decisions about genetic counseling and testing for inherited gene mutations. We kicked off the effort by launching a brief survey to better understand how women with ovarian and related cancers make decisions about genetic … + read more

May 27, 2016

Blog: What Do the New Guidelines from the National Comprehensive Cancer Network Mean For You?

by Lisa Rezende, PhD People with hereditary cancer face many decisions, such as whether or not to have genetic testing, choosing the best type and frequency of cancer screening, and whether or not to manage cancer risk through surgery. Health care providers look to national guidelines to give their patients advice as they make these … + read more

May 19, 2016

Updates in Research on Treating Hereditary Cancers

Note: This post which was originally published 08/4/15 was just updated on 05/19/16. In December 2014, the FDA approved the first targeted therapy for people with BRCA mutations. Lynparza, a type of medication known as a PARP inhibitor, was approved for women with a BRCA mutation to treat advanced ovarian, fallopian tube, or primary peritoneal cancer that has progressed after … + read more

April 25, 2016

Receive Personalized Resources and Support Quickly and Easily Through FORCE’s New Peer Navigation Program

by Wendy Demming, FORCE Peer Navigator Volunteer I wanted to be a Peer Navigator because it is important for me to help others who are going through an overwhelming diagnosis. I remember being desperate for credible information, and wanting to talk to others who had been in a similar situation. I was so grateful when … + read more

March 17, 2016

Ovarian Cancer Survivors with a Negative Genetic Test Result in the Past May Benefit from Additional Genetic Counseling/Testing

KNOW MORE is a new campaign designed by FORCE to inform every woman diagnosed with ovarian, fallopian tube, and primary peritoneal cancer about national guidelines on genetic counseling and testing for inherited gene mutations. We kicked off the campaign by launching a brief survey to better understand how women with ovarian cancer make decisions around … + read more

March 3, 2016

OlympiA: A Landmark Breast Cancer PARP Inhibitor Clinical Trial

by Sue Friedman Great progress has been made since the identification of the BRCA1 and BRCA2 genes and their link to causing breast, ovarian, pancreatic and other cancers. Over the last two decades, researchers have studied how BRCA mutations cause cancer in an effort to develop new treatments. In December 2014, Lynparza, (olaparib), a type … + read more

Connect with others.

Call our Helpline

Our helpline offers peer support for people concerned about hereditary cancer. All calls are confidential. Call any time.

Join a Local Group

FORCE has outreach groups throughout the United States and in Essex, United Kingdom that meet periodically to offer peer support, and share resources.

FORCE:Facing Our Risk of Cancer Empowered