ScienceDaily: "Triple-negative: Genes associated with risk for aggressive breast cancer"
- The only source is the senior author of the study.
- The article clearly describes the study design.
- The article touches on the fact that this new research may result in changes in NCCN guidelines.
USA Today: "Researchers identify genes linked to aggressive breast cancer"
- This is a very short article covering the new research. The headline and lede match the reporting.
- No sources other than the senior author were included.
- Because of the brevity of this article, it is likely very difficult for a lay reader to discern exactly what was tested and the implications of the results.
- It is not clear in this article if mutations are somatic or inherited.
abcNews: "New genes discovered that may increase risk for triple-negative breast cancer"
- The headline more or less matches what the article claims.
- The lede is vague in that it states, “…identified specific genes that go with an increased risk for developing triple-negative breast cancer.” It is unclear what “go with” implies.
- The article states, “There are different types of breast cancer, which are determined by the specific cells in the breast that are affected, according to the American Cancer Society.” While this is true, it has nothing to do with TNBC. TNBC arises from the epithelial cells that line the breast ducts as do other subtypes of breast cancers. Lobular breast cancer arises from a different type of cell. It is not the cell type that is different in the study reported but the markers on the cell.
- The article muddies the difference between inherited mutations and markers such as ER, PR, and HER2-receptors normally found on breast epithelial cells.
- There is no distinction between tumor DNA changes and inherited mutations.
- A lay reader would be very confused by this article.