- This study is most relevant to male young breast cancer survivors, who had the highest rates of double mastectomy.
- Although the research is specific to men with breast cancer, the study did not look at whether the men with breast cancer had an inherited mutation.
- The research looked at survival outcomes, but not incidence of a second breast cancer or recurrence.
- Mastectomy should be an individualized decision between the patient and the health care provider.
Strength of Science: Medium
- This research study used an appropriate research design.
- However, it is a retrospective study, which makes it a little weaker. While the experiments do answer the questions the researchers are asking, the results are very generalized.
- By looking only at male survival rates and failing to also look at recurrence rates, researchers are unable to consider the possibility that double mastectomy may be decreasing the occurrence of a second cancer, helping these patients avoid further treatment.
- Additionally, while they do see an increase in the rate of double mastectomy in men (the rate doubled), the absolute increase is relatively small because double mastectomy is relatively rare in men.
- Researchers were not able to look at BRCA status, which may have influenced double mastectomy rates.