- This study was a survey of Society of Breast Imaging Fellows. Surveys of this type have many limitations including bias in those who responded to the survey request, the fact that some responses relied on recall of facts, and importantly, the authors do not know why breast cancer patients may have not been treated for their disease.
- Because of the many limitations in the study design, some of the conclusions need to be further studied and confirmed by more robust protocols.
- Some of the conclusions the authors make cannot be made given the available data. While these conclusions may indeed be true, they can only be made by including analysis of patient data for those patients who were identified as not receiving treatment for their breast cancer.
- This study nevertheless provides preliminary data on the controversial assumption that some breast cancers spontaneously disappear or regress on their own.