XRAYS Quarterly Digest

XRAYS: Making Sense of Cancer Headlines
Fall Edition

XRAYS Quarterly Digest For Winter 2019

A compilation of the past quarter's reviewed articles.

FORCE's eXamining the Relevance of Articles for Young Survivors (XRAYS) program, is a reliable resource designed to help young breast cancer survivors and high-risk women navigate through breast cancer research related news and information

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STUDY: Gaps in information about breast cancer risk and prevention impact African American women

A study showed that African American women experienced greater burdens in obtaining information at each step compared to white women. Racial differences in preventive choices correlated with differences in information and provider access. (3/14/19)

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STUDY: Prevalence of BRCA founder mutations in Bahamian women

Summary:

Population-based testing for BRCA mutations can detect mutation carriers who do not have a family history of cancer. This study reviewed whether population-based testing is an effective approach in the Bahamas which has the highest known frequency of BRCA mutations among breast cancer patients. (3/4/19)

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STUDY: Breast cancer implant study suggests links with illness but has serious flaws

Summary

An article in the Annals of Surgery, researchers conclude that their work supports an association between silicone breast implants and a range of conditions. This journal article was accompanied by two editorials in which experts voiced their disagreement with the way the analysis was performed and the conclusions of the authors. (2/21/19)

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ARTICLE: Promise of a cure for cancer is too good to be true

Summary:

The Jerusalem Post published an article titled, “A cure for cancer?  Israeli scientists may have found one.” The story profiled a small Israeli company called Accelerated Evolution Biotechnologies that has been working on developing new cancer treatments since 2000. The article relied almost entirely on an interview with the company’s chairperson of the board who made a series of unsubstantiated claims that included that, in a year’s time, the company will offer a complete cure for cancer. (2/12/19)

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ARTICLE: The cost of cancer care and impact of financial hardship on treatment

Summary:

Several recent studies on the cost of cancer care show the negative effects on cancer patients. In this XRAYS we review a recent article by Kaiser Health News and associated studies about the financial impact of breast cancer treatment and cost of precision medicine. (2/8/19)

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STUDY: The impact of palbociclib (Ibrance) on overall survival for metastatic breast cancer patients in the PALOMA-3 trial

Summary: 

The PALOMA-3 clinical trial showed that a new CDK4/6 inhibitor in combination therapy improved progression-free survival of women treated for hormone receptor-positive, HER2-negative advanced or metastatic breast cancer in women with prior disease progression after endocrine therapy. This XRAYS reviews a newly published study in the New England Journal of Medicine that looks at overall survival in the original PALOMA-3 study. (1/23/19)

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STUDY: FORCE online survey: What breast cancer information do young women want and where do they look for it?

Summary:

FORCE developed the CDC-funded Examining Relevance of Articles to Young Survivors or XRAYS program to help young breast cancer survivors and those at high-risk better understand media coverage about new breast cancer research. To ensure that the program would be responsive to users’ needs, FORCE designed a web-based survey to assess where young women look for information about breast cancer and to learn their unmet information needs.  The results of this survey were published in the journal Health Communications. (1/18/19)

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STUDY: Improving outcomes for young women with breast cancer: fertility and childbearing issues

Fertility issues and family planning decisions are prominent concerns for young women with breast cancer. This XRAYS looks at Dr. Ann Partridge’s presentation at the 2018 San Antonio Breast Cancer symposium. Her talk, “Breast cancer in young women: Understanding differences to improve outcomes," focused on initial findings from the Young Women's Breast Cancer Study. Dr. Partridge’s research continues in the currently enrolling POSITIVE trial which tests whether women can safely interrupt adjuvant endocrine therapy in order to get pregnant. (1/7/19)

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