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FORCE's eXamining the Relevance of Articles for You (XRAY) program looks behind the headlines of cancer news to help you understand what the research means for you. XRAY is a reliable source of hereditary cancer research-related news and information.
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1 through 10 of 12

Relevance: Medium-High

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Strength of Science: Medium-High

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Research Timeline: Post Approval

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Study : Knowing about an inherited BRCA mutation improves outcomes for women with breast cancer

Most relevant for: Young women with, or at high risk for an inherited BRCA mutation

Inherited mutations in the BRCA1 and BRCA2 genes are linked to a high lifetime risk of breast and other cancers. This study shows that women who know that they have a BRCA mutation before they are diagnosed with breast cancer have improved outcomes including diagnosis at earlier stages and improved overall survival. (10/26/20)

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Knowing about an inherited BRCA mutation improves outcomes for women with breast cancer

Relevance: Medium-High

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Strength of Science: Medium-High

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Research Timeline: Human Research

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Study : New imaging technology shows promise in detecting of spread of prostate cancer

Most relevant for: Men with high-risk prostate cancer

A new imaging technique is currently being tested to see if it can detect the spread of prostate cancer sooner than standard imaging. Two clinical trials show that the new technique can detect the spread of prostate cancer in men who are newly diagnosed and in men whose cancer returns after treatment. (10/16/20)

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New imaging technology shows promise in detecting of spread of prostate cancer

Relevance: High

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Strength of Science: Medium-High

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Research Timeline: Post Approval

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Study : MRI or mammograms for detecting breast cancer in families with unknown genetic mutations?

Most relevant for: People with a personal or family history of cancer where no mutation has been found

MRI and mammograms are used together to detect breast cancer in high-risk women who test positive for a BRCA or other gene mutation that increases the risk for breast cancer. For women with a family history of breast cancer but no known genetic mutation, increased screening is recommended. But what method is best? A recent clinical trial in the Netherlands compared MRI and mammography for this population. (8/15/19)

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MRI or mammograms for detecting breast cancer in families with unknown genetic mutations?

Relevance: Medium-High

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Strength of Science: Medium-High

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Study : Diagnosis and treatment delays in young women with breast cancer

Most relevant for: Young women who find a breast lump and young women newly-diagnosed with breast cancer

Young women are more likely to have delays in a breast cancer diagnosis and treatment.  Factors that affect these delays include pregnancy, breastfeeding, financial concerns and having a family history of breast or ovarian cancer. (8/5/19)

Este artículo está disponible en español.

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Diagnosis and treatment delays in young women with breast cancer

Relevance: High

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Strength of Science: Medium-High

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Research Timeline: Post Approval

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Study : Gaps in information about breast cancer risk and prevention impact African American women

Most relevant for: African American women who are at high risk for breast cancer

A study showed that African American women with increased breast cancer risk experienced greater burdens in obtaining information at each step compared to white women. Racial differences in preventive choices correlated with differences in information and provider access. (3/14/19)

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Gaps in information about breast cancer risk and prevention impact African American women

Relevance: High

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Strength of Science: High

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Research Timeline: Post Approval

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Study : Should biannual MRIs replace annual mammograms in high-risk women?

Most relevant for: Women at increased risk for breast cancer due to an inherited mutation

The risk of breast cancer is exceptionally high in women who have a personal or family history of breast cancer or who carry a mutation in BRCA or certain other genes. More frequent screening is one strategy for early detection of breast cancer for these women. Study results presented at the 2017 San Antonio Breast Cancer Symposium suggest that MRI screening every 6 months may be more effective than the currently recommended annual breast MRI and annual mammogram in detecting early stage breast cancers-which are more treatable-in high-risk women. (2/1/18)

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Should biannual MRIs replace annual mammograms in high-risk women?

Relevance: Medium-High

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Quality of Writing: High

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Article : Dense breasts and mammograms: Jill Goodacre’s story

Most relevant for: Women with dense breast tissue on mammograms

Korin Miller’s piece for SELF magazine focuses on why women with dense breasts may need more than a screening mammogram. Miller highlights the recent story in People magazine of Jill Goodacre, a former Victoria’s Secret model and the wife of recording artist and talk show host Harry Connick Jr. Goodacre told of her breast cancer diagnosis 5 years ago after having additional screening of her dense breast tissue following a normal mammogram.  (12/8/17)

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Dense breasts and mammograms: Jill Goodacre’s story

Relevance: Medium

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Strength of Science: Medium

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Research Timeline: Post Approval

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Study : Do physicians recommend breast cancer screenings based on guidelines?

Most relevant for: Women at average risk for breast cancer

Several guidelines help physicians decide when a woman should begin screening for breast cancer and how often she should be screened. However, are these guidelines put into use in the clinic? (8/8/17)

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Do physicians recommend breast cancer screenings based on guidelines?

Relevance: Medium-High

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Strength of Science: Medium-Low

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Study : Routine breast cancer screening leads to overdiagnosis

Most relevant for: Women at average risk for breast cancer

Routine breast cancer screening for women of average risk has been controversial for many years because some believe that the benefits do not outweigh the risks. Recent headlines covering a study in Denmark suggests that routine breast cancer screening leads to “overdiagnosis” of breast cancer. (4/4/17)

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Routine breast cancer screening leads to overdiagnosis

Relevance: Medium

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Strength of Science: Medium

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Study : Breast cancer screening should be tailored to a woman’s risk factors and breast density

Most relevant for: Women who are at high risk for breast cancer due to family history, dense breasts, LCIS, or multiple biopsies

The United States Preventative Services Task Force (USPSTF) recommends a screening mammogram every other year for women ages 50-74 who are at average risk for breast cancer. But do all patients in this category benefit from this screening regimen?

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Breast cancer screening should be tailored to a woman’s risk factors and breast density