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FORCE's eXamining the Relevance of Articles for You (XRAY) program looks behind the headlines of cancer news to help you understand what the research means for you. XRAY is a reliable source of hereditary cancer research-related news and information.
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11 through 20 of 25

Relevance: Medium-High

Strength of Science: Medium-High

Research Timeline: Post Approval

Study : Prevalence of BRCA founder mutations in Bahamian women

Most relevant for: Bahamanian women

The Bahamas has the highest known frequency of BRCA mutations among people diagnosed with breast cancer. This study reviewed whether population-based BRCA testing (testing everyone regardless of family or personal history of cancer) would be an effective approach for finding mutation carriers in the Bahamas. (3/4/19)

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Relevance: Medium-High

Strength of Science: High

Research Timeline: Post Approval

Study : Inherited breast cancer in Nigerian women

Most relevant for: Nigerian women or women of Nigerian descent who have breast cancer

A new study shows that among Nigerian women, one in eight cases of breast cancer is due to an inherited mutation in BRCA1, BRCA2, PALB2 or TP53. (12/5/18)

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Relevance: High

Quality of Writing: High

Article : The importance of racial diversity in clinical trials

Most relevant for: People who are a member of a racial or ethnic minority group

This article by journalists Caroline Chen and Riley Wong looks at racial disparities between participation in clinical trials and the population of people with cancer. (11/6/18)

Este artículo está disponible en español.

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Relevance: High

Strength of Science: Medium-High

Research Timeline: Post Approval

Study : Surgeon attitude impacts rate of genetic testing after a breast cancer diagnosis

Most relevant for: Young women diagnosed with breast cancer who have not yet had genetic testing

A study in JAMA Surgery this year examined the factors that impact genetic testing after a breast cancer diagnosis. This study suggests that the attitudes of attending surgeons about genetic testing have the most impact on whether patients receive testing. (10/6/18)

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Relevance: High

Strength of Science: High

Research Timeline: Post Approval

Study : Disparities in research impact breast screening guidelines

Most relevant for: Women at average risk for breast cancer

For women at average risk of breast cancer, the United States Preventive Services Task Force (USPSTF) currently recommends beginning annual breast cancer screening at age 50. However, because these guidelines are largely based on data from white women, they may not be sensitive to racial differences.  A new study assesses the age distribution of breast cancer cases across race/ethnicity in the U.S. (6/21/18)

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Relevance: High

Quality of Writing: High

Article : The right not to know when not knowing is dangerous

Most relevant for: People with Icelandic heritage

Healthcare providers are bound by the guiding principle of doing no harm. But how does this concept apply to their patients who have not consented to genetic testing or who do not want to know their results? In that case, is providing test results more harmful or not? Anna Clausen explores these issues in the context of breast cancer gene testing in her Global Health Now article “The Right Not to Know: When Ignorance is Bliss but Deadly.” (4/20/18)

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Relevance: Medium

Research Timeline: Post Approval

Update : FDA approves at-home test kits for inherited cancer: how useful are they?

Most relevant for: People who are considering or have had direct-to-consumer testing through 23andMe

Genetic testing for health conditions (such as risk for cancer) typically requires a prescription from a doctor. Until recently, direct-to-consumer (DTC) genetic testing has focused on tests to learn your ancestry and find of unknown branches of family trees. A laboratory called 23andMe that provides direct-to-consumer genetic testing has been given FDA approval to report results for 3 mutations found in the BRCA1 and BRCA2 genes. The FDA statement provides details about this approval and warns people about the limitations of the 23andMe test. (03/19/18)

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Relevance: High

Strength of Science: Medium

Study : Alcohol and breast cancer risk in African American women

Most relevant for: African American women who would like to lower their breast cancer risk

The link between alcohol intake and breast cancer is well known, but most studies have involved only White women. Recently, a large study of more than 22,000 African American (AA) women found that similar to White women, increased alcohol consumption is associated with a greater risk of breast cancer. (10/27/17)

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Relevance: Medium-High

Strength of Science: Medium

Study : Beauty and the breast: hair product use and breast cancer risk

Most relevant for: Women who use hair products who are concerned about their risk for breast cancer

Past studies using mostly animal models showed a link between use of hair products (dyes, straighteners and relaxers) and increased risk of certain cancers. In this study, researchers looked at data on hair product use among African-American (AA) and White women to see if certain types of hair products increased breast cancer risk, and how that risk might differ between race and breast cancer hormone status. (9/27/2017)

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Relevance: Medium

Strength of Science: Medium

Study : Breast cancer rates are rapidly increasing among Asian women in California

Most relevant for: Asian American women

The majority of racial groups in the United States have seen declines in breast cancer rates. However, this study provides new insights into the patterns of breast cancer rates in Asian American subgroups in California. Using 26 years of data, this research found that breast cancer is rapidly increasing among this population, contrasting to a decline in rates among non-Hispanic white women in California and nationwide. (8/15/17)

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