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FORCE's eXamining the Relevance of Articles for You (XRAY) program looks behind the headlines of cancer news to help you understand what the research means for you. XRAY is a reliable source of hereditary cancer research-related news and information.
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In portal: Breast Cancer, Categories Prevention, Screening

11 through 20 of 75

Relevance: Medium-High

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Article : Breast cancer risk for transgender men with inherited mutations

Relevance: Medium-High

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Most relevant for: Transgender men with an inherited mutation

There is little information related to the risks and treatment options for transgender men and nonbinary people who are at high-risk for breast cancer due to an inherited BRCA1 or BRCA2 mutation. We review an expert viewpoint on the implications of a BRCA mutation for transgender men undergoing breast removal as part of their gender-affirming care plan. (posted 5/19/22)

Este artículo está disponible en español.

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Relevance: Medium-High

Strength of Science: Medium-High

Research Timeline: Post Approval

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Study : New tool to predict breast cancer risk for Black women

Relevance: Medium-High

Strength of Science: Medium-High

Research Timeline: Post Approval

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Most relevant for: Black women in the U.S.

An important part of making decisions about breast cancer screening and prevention is knowing your breast cancer risk. Specific tools are used to identify people who would benefit from early and/or additional screening and chemoprevention or those who would most benefit from genetic counseling and testing. Because these tools were developed using data mostly from white women, they are unable to predict cancer risk as well for Black women. To begin to address these gaps, researchers developed a new tool specifically designed to predict breast cancer risk for Black women. This tool has been shown to work well, especially for younger Black women. (posted 3/22/2022) Este artículo está disponible en español.

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Relevance: High

Quality of Writing: Medium-High

Research Timeline: Post Approval

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Article : Chris Evert's ovarian cancer diagnosis highlights the importance of genetic counseling and testing

Relevance: High

Quality of Writing: Medium-High

Research Timeline: Post Approval

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Most relevant for: People with genetic test result called a VUS

Tennis star Chris Evert shared her story about a change in her sister's genetic test results that led Ms. Evert to have genetic testing and her decision to have her ovaries removed to lower her cancer risk. Ovarian cancer was found at the time of Ms. Evert’s surgery, but fortunately, it was caught early. Her story highlights the importance of genetic counseling, testing and post-testing follow-up with experts. (Posted 2/8/22). Este artículo está disponible en español.

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Relevance: Medium-Low

Research Timeline: Human Research

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Update : Blood tests called liquid biopsies for cancer screening, monitoring and treatment

Relevance: Medium-Low

Research Timeline: Human Research

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Most relevant for: People considering a liquid biopsy to screen for cancer

Could a simple blood test change cancer detection, treatment and monitoring? Several companies are offering a type of blood test known as a liquid biopsy to detect multiple cancers at their earliest stages, monitor response to treatment and help choose the best treatment. Although progress has been made using liquid biopsies to treat cancer, these tests have not yet been shown to detect cancer early enough to save lives. (posted 9/29/21)

Este artículo está disponible en español.

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Relevance: High

Strength of Science: High

Research Timeline: Post Approval

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Study : Cancer risks of people with inherited PALB2 mutations

Relevance: High

Strength of Science: High

Research Timeline: Post Approval

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Most relevant for: people with inherited PALB2 mutations

In the largest study of people with inherited PALB2 mutations to date, the gene was linked to increased lifetime risk of breast cancer in women and men, ovarian and pancreatic cancer but not prostate or colorectal cancer. (posted 7/1/21)

Este artículo está disponible en español.

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Relevance: High

Strength of Science: High

Research Timeline: Post Approval

Study : Birth control pills may offer long-term protection against endometrial and ovarian cancer

Relevance: High

Strength of Science: High

Research Timeline: Post Approval

Most relevant for: People concerned about endometrial, ovarian or breast cancer risk

A large study showed that birth control pills may protect against endometrial and ovarian cancers, even years after use was discontinued. (posted 6/1/21)

Este artículo está disponible en español.

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Relevance: Medium

Research Timeline: Human Research

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Update : FDA allows testing of a vaccine designed to prevent breast cancer

Relevance: Medium

Research Timeline: Human Research

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Most relevant for: Patients with non-metastatic triple-negative breast cancer at high risk of recurrence.

Scientists have been working for many years to develop a vaccine that will prevent breast cancer. The FDA recently announced that the first clinical trial to test a preventive breast cancer vaccine can begin. This vaccine is the result of over a decade of research in animals and human cells. While researchers will first test the vaccine in women who have breast cancer, they hope to use this vaccine in the future to prevent breast cancer.  (posted 5/25/21)

THIS INFORMATION HAS BEEN UPDATED on 10/12/2021: The clinical trial discussed in this XRAY review has begun recruiting participants.  Researchers hope to enroll 24 patients with non-metastatic triple-negative breast cancer. The trial is being conducted at the Cleveland Clinic in Cleveland, Ohio. More information on this trial can be found here.

Este artículo está disponible en español.

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Relevance: High

Research Timeline: Post Approval

Guideline : Expert guidelines on COVID-19 vaccines and timing of breast screening tests

Relevance: High

Research Timeline: Post Approval

Most relevant for: People considering screening mammography after getting a COVID-19 vaccine.

COVID-19 vaccines work by helping the immune system destroy the virus. Lymph nodes are an important part of the immune system. COVID-19 vaccines may cause temporary swelling in some lymph nodes, which may look suspicious on a mammogram.  The Society for Breast Imaging and other professional organizations have released recommendations for the timing of mammograms after COVID-19 vaccines.  (3/30/21)

Este artículo está disponible en español.

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Relevance: Medium-High

Strength of Science: Medium-High

Research Timeline: Post Approval

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Study : Patient outcomes and experiences of going flat

Relevance: Medium-High

Strength of Science: Medium-High

Research Timeline: Post Approval

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Most relevant for: Women considering mastectomy without breast reconstruction.

Some patients with early-stage breast cancer or those considering risk-reducing surgery may choose mastectomy without reconstruction. This is often referred to as “going flat.” The results of this study suggest that surgeons play a significant role in supporting a patient’s decision to go flat. (3/23/2021)

Este artículo está disponible en español.

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Relevance: Medium-High

Strength of Science: Medium-High

Research Timeline: Post Approval

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Study : Body Mass Index (BMI) may affect how well aspirin use protects against colorectal and ovarian cancer

Relevance: Medium-High

Strength of Science: Medium-High

Research Timeline: Post Approval

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Most relevant for: People concerned about their risk of colorectal or ovarian cancer.

This study looked at the impact of daily aspirin use on the risk for many types of cancers and whether this effect can be modified by risk factors such as obesity, smoking, physical inactivity or a family history of cancer. Daily aspirin use: 

  • lowered the risk for colorectal cancer, but this effect was lost as Body Mass Index (BMI) increased.
  • lowered the risk of ovarian cancer risk among obese women.
  • offered little or no protection against breast, endometrial or advanced prostate cancer.

(posted 3/19/21)

Este artículo está disponible en español.

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