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FORCE's eXamining the Relevance of Articles for You (XRAY) program looks behind the headlines of cancer news to help you understand what the research means for you. XRAY is a reliable source of hereditary cancer research-related news and information.
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1 through 10 of 217

Relevance: High

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Strength of Science: Medium-High

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Research Timeline: Post Approval

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Study : Women can have safe pregnancies after breast cancer treatment

Most relevant for: Women who have had breast cancer who are considering pregnancy.

In a large analysis of all published studies to date, most women who become pregnant after breast cancer treatment had safe pregnancies, with no increase in their cancer recurrence risk. Infants of mothers treated for breast cancer were more likely to have low birth weight, preterm birth and small size at birth but there was no increase in birth defects. Breast cancer survivors who became pregnant had a similar risk of recurrence and survival as survivors who did not become pregnant. (posted 6/24/21)

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Women can have safe pregnancies after breast cancer treatment

Relevance: High

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Strength of Science: High

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Research Timeline: Post Approval

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Study : Birth control pills may offer long-term protection against endometrial and ovarian cancer

Most relevant for: People concerned about endometrial, ovarian or breast cancer risk

A large study showed that birth control pills may protect against endometrial and ovarian cancers, even years after use was discontinued. (posted 6/1/21)

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Birth control pills may offer long-term protection against endometrial and ovarian cancer

Relevance: Medium

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Research Timeline: Human Research

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Update : FDA allows testing of a vaccine designed to prevent breast cancer

Most relevant for: Patients with non-metastatic triple-negative breast cancer at high risk of recurrence.

Scientists have been working for many years to develop a vaccine that will prevent breast cancer. The FDA recently announced that the first clinical trial to test a preventive breast cancer vaccine can begin. This vaccine is the result of over a decade of research in animals and human cells. While researchers will first test the vaccine in women who have breast cancer, they hope to use this vaccine in the future to prevent breast cancer.  (posted 5/25/21)

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FDA allows testing of a vaccine designed to prevent breast cancer

Relevance: High

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Strength of Science: Medium-High

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Research Timeline: Post Approval

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Update : Immunotherapy dostarlimab gains FDA approval for treatment of recurrent and advanced endometrial cancer

Most relevant for: People with recurrent or advanced endometrial cancer

The FDA has given accelerated approval for the immunotherapy agent dostarlimab (Jemperli) to treat recurrent and advanced endometrial cancer that has a biomarker called mismatch repair deficiency (dMMR). This adds a new treatment option for people with recurrent or advanced endometrial cancer. (posted 5/18/21)

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Immunotherapy dostarlimab gains FDA approval for treatment of recurrent and advanced endometrial cancer

Relevance: High

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Strength of Science: High

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Research Timeline: Post Approval

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Study : Daily high-dose aspirin taken for at least 2 years reduces the risk of colorectal cancer but not other cancers in people with Lynch syndrome

Most relevant for: People with Lynch syndrome

Research has shown that daily aspirin use can reduce the risk of colon and other cancers. The Cancer Prevention Program 2 (CaPP2) study looked at the effect of daily aspirin in patients with Lynch syndrome. After 10 years of follow-up, the results showed that taking daily aspirin for two years reduced the frequency of colon cancer in patients with Lynch syndrome, and importantly, did not result in an increase in side-effects or complications. No benefit was seen for other Lynch syndrome-related cancers, including endometrial cancer. (5/17/21)

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Daily high-dose aspirin taken for at least 2 years reduces the risk of colorectal cancer but not other cancers in people with Lynch syndrome

Relevance: Medium-High

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Strength of Science: High

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Update : Cancer disparities: Colorectal cancer in African Americans

Most relevant for: African Americans concerned about colorectal cancer

The American Association for Cancer Research (AACR) released a 2020 report about cancer disparities among racial and ethnic groups in the United States. In this XRAY review, we highlight data from the report about the burden of colorectal cancer in African Americans, who have the highest rates of diagnosis and death related to the disease among all racial and ethnic groups. (Posted 4/27/21)

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Cancer disparities: Colorectal cancer in African Americans

Relevance: High

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Strength of Science: Medium-High

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Research Timeline: Post Approval

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Study : Expanded access to Medicaid coverage under the Affordable Care Act is linked to reduced cancer mortality

Most relevant for: People with breast, colorectal or lung cancer.

In 2014 the Affordable Care Act expanded Medicaid coverage. How did this affect healthcare for cancer patients? This study shows that deaths from breast, colorectal and lung cancer are lower in states that chose to expand Medicaid compared to states that did not. Early diagnosis was linked to lower death rates. This suggests that increased healthcare access may lead to earlier cancer detection and better outcomes, including lower mortality. (3/31/2021)

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Expanded access to Medicaid coverage under the Affordable Care Act is linked to reduced cancer mortality

Relevance: High

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Research Timeline: Post Approval

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Guideline : Expert guidelines on COVID-19 vaccines and timing of breast screening tests

Most relevant for: People considering screening mammography after getting a COVID-19 vaccine.

COVID-19 vaccines work by helping the immune system destroy the virus. Lymph nodes are an important part of the immune system. COVID-19 vaccines may cause temporary swelling in some lymph nodes, which may look suspicious on a mammogram.  The Society for Breast Imaging and other professional organizations have released recommendations for the timing of mammograms after COVID-19 vaccines.  (3/30/21)

Este artículo está disponible en español.

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Expert guidelines on COVID-19 vaccines and timing of breast screening tests

Relevance: Medium-High

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Strength of Science: Medium-High

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Research Timeline: Post Approval

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Study : Patient outcomes and experiences of going flat

Most relevant for: Women considering mastectomy without breast reconstruction.

Some patients with early-stage breast cancer or those considering risk-reducing surgery may choose mastectomy without reconstruction. This is often referred to as “going flat.” The results of this study suggest that surgeons play a significant role in supporting a patient’s decision to go flat. (3/23/2021)

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Patient outcomes and experiences of going flat

Relevance: Medium-High

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Strength of Science: Medium-High

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Research Timeline: Post Approval

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Study : Body Mass Index (BMI) may affect how well aspirin use protects against colorectal and ovarian cancer

Most relevant for: People concerned about their risk of colorectal or ovarian cancer.

This study looked at the impact of daily aspirin use for lowering the risk for multiple types of cancers and whether this risk reduction can be modified by cancer risk factors such as obesity, smoking, physical inactivity or a family history of cancer. (3/19/21)

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Body Mass Index (BMI) may affect how well aspirin use protects against colorectal and ovarian cancer