Categories Palliative Care, Quality of Life, Survivorship



Relevance: Medium
Most relevant for: People with Li-Fraumeni syndrome
Personal Story: Living a full life with Li-Fraumeni syndrome
This XRAY review is about a five-time cancer survivor who has an inherited mutation in the TP53 gene. People with inherited mutations in TP53 have Li-Fraumeni syndrome, which is linked to a very high lifetime risk for many types of cancer. Here we share his inspiring story and provide more information on Li-Fraumeni syndrome. (Posted 4/16/24)
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Relevance: Medium-High
Most relevant for: People with breast cancer or metastatic breast cancer in sexual or intimate relationships and their partners
Topic: Sex and intimacy after breast cancer
A breast cancer diagnosis and treatment can affect relationships with romantic partners. This review highlights two studies that looked at how people with breast cancer and their partners are affected, how they cope, how best to communicate with each other and how to talk with healthcare providers about concerns related to cancer and sexuality. (Posted 8/8/23)
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Relevance: Medium
Most relevant for: Women considering risk-reducing removal of both ovaries
Study: Early removal of ovaries may be linked to small increase in risk of Parkinson’s disease in later life
The lifetime risk of developing Parkinson’s disease is low. However, having surgery to remove both ovaries before natural menopause can slightly increase the risk of Parkinson's disease later in life. Researchers studied over 20 years of medical records, which confirmed this small increase in risk, particularly for women who have their ovaries removed before age 43. (Posted 5/3/23)
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Relevance: High
Most relevant for: People with early-stage breast cancer who are post-menopausal
Study: Treatment to reduce bone fractures also improves breast cancer survival in postmenopausal people
A large study looked at the effects of adding the bone-protective drug denosumab (Prolia), to standard hormone therapy for the treatment of early-stage, postmenopausal, HR-positive breast cancer. The researchers found that adding denosumab to aromatase inhibitor hormonal therapy improved bone health, disease-free survival and overall survival. (Posted 2/27/23)
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Relevance: High
Most relevant for: People with advanced ovarian cancer
Study: What influences aggressive end-of-life care for ovarian cancer?
Aggressive medical treatment is often given to people with terminal ovarian cancer when prior treatment has stopped working. This aggressive end-of-life treatment conflicts with clinical guidelines, may increase pain and suffering and does not extend life. This study found that the end-of-life care that a person with ovarian cancer receives is influenced by their doctors. (Posted 1/3/23)
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Relevance: Medium-High
Most relevant for: Men with breast cancer
Study: Male breast cancer: Patient and surgeon experiences
By surveying male breast cancer patients and the surgeons who treat them, researchers gained insight into the experiences of both groups, shedding light on an important issue for men with breast cancer. (Posted 12/22/22)
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Relevance: High
Most relevant for: Americans Indians and Alaska Natives
Topic: Cancer disparities in American Indian and Alaska Native populations
The American Cancer Society released a special section in their 2022 Cancer Facts & Figures report that discussed cancer disparities in American Indian and Alaska Native populations in the United States. This review highlights the special section’s main points, including disparities in cancer screening, diagnosis and survival rates in native communities, as well as factors contributing to those disparities. (Posted 12/20/22)
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Relevance: Medium-High
Most relevant for: People currently undergoing treatment for cancer
Guideline: Guidelines on exercise, diet, and weight during cancer treatment
Most professional guidelines on exercise, diet and weight management have focused on the health of the general population and cancer survivors. The American Society of Clinical Oncology (ASCO) has now published evidence-based recommendations for exercise, diet and weight specifically for people who are in active treatment for cancer. (Posted 11/29/22) Este artículo está disponible en español.
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Relevance: High
Most relevant for: People with pancreatic cancer who are dealing with related pain.
Update: Strategies for managing pancreatic cancer pain
Abdominal pain is often a severe, ongoing symptom of pancreatic cancer, yet little research has been done on how to best reduce this pain. The authors of this review discuss current strategies for managing cancer-related pain and their effectiveness. (Posted 10/31/22)
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Relevance: Medium-High
Most relevant for: Mothers who have had genetic testing for BRCA1 or BRCA2 whether or not they have been diagnosed with breast or ovarian cancer
Study: Teens and young adults respond well to learning about familial cancer risk
Little is known about how awareness of hereditary cancer in a high-risk family affects the quality of life of teens and young adults. This study looked at the lifestyle choices, cancer awareness and quality of life of adolescents and young adults whose mothers had undergone testing for a BRCA mutation. (Posted 10/11/2022) Este artículo está disponible en español.
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