Mutations in familial melanoma genes and cancer risk
https://www.facingourrisk.org/XRAY/melanoma-genes-and-genetic-testing
Researchers studied nearly 700,000 people from the United States and the United Kingdom to learn how common mutations in familial melanoma genes are in the general population. They found that these mutations may be more common than previously estimated and were often found in people who developed melanoma at a young age or who had more than one melanoma. These findings suggest that some people with melanoma may benefit from discussing genetic counseling and testing with their healthcare provider. (posted 7/28/2026)
By: Piri Welcsh, PhD
Reviewed by: Michael R Sargen, MD
Questions To Ask Your Health Care Provider
- Based on my personal and family history, should I consider genetic testing for hereditary melanoma?
- Would a referral to a genetic counselor be appropriate for me?
- Could a mutation in a melanoma gene also affect my risk for other cancers?
- Are there steps I should take now to lower my melanoma risk, regardless of whether I have genetic testing?
About FORCE
FORCE is a national nonprofit organization, established in 1999. Our mission is to improve the lives of individuals and families affected by adult hereditary cancers.