Cancer risk associated with inherited mutations in Lynch syndrome genes
Full article:

Lynch syndrome is the most common inherited cause of cancer affecting about 1 in 300 people. People with Lynch syndrome have an increased risk of colorectal endometrial and other cancers. A large study followed people with mutations in the Lynch syndrome genes MLH1, MSH2, MSH6 and PMS2 to determine the risk of other types of cancer. (2/21/20)

Questions To Ask Your Health Care Provider

Open Clinical Trials

The following studies are enrolling people with a mutation linked to Lynch syndrome:

The following screening and prevention studies are open to people with Lynch syndrome. 

Colorectal cancer

Gynecologic cancers

Prostate cancer

Pancreatic cancer

Other clinical trials for patients with endometrial cancer can be found here.



FORCE is a national nonprofit organization, established in 1999. Our mission is to improve the lives of individuals and families affected by adult hereditary cancers.