Joining FORCES is the FORCE newsletter with news, views and supportive information for individuals concerned about hereditary breast and ovarian cancer.
by Lisa Rezende, Ph.D.
Risk-reducing salpingo-oophorectomy (RRSO) has been shown to decrease the rate of ovarian cancer and increase lifespan in women with BRCA mutations, but the surgery shifts premenopausal women into immediate menopause. Dr. Susan Domchek (Basser Center for BRCA) and Dr. Neill Epperson (Director, Penn Center for Women’s Behavioral Wellness) presented the latest research on the long-term effects of menopause.
Dr. Domchek’s study of the long-term consequences of surgical menopause after RRSO found that more than 50% of patients had issues with bone loss, stress, hot flashes, decreased libido, attention problems, and sleep loss.
Dr. Epperson discussed the “post-RRSO brain,” detailing the cognitive effects of early menopause on women who undergo RRSO. She noted that:
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