Joining FORCES is the FORCE newsletter with news, views and supportive information for individuals concerned about hereditary breast and ovarian cancer.
by Sue Friedman
Presenter: Steven Narod, MD, FRCP, Canada Research Chair in Breast Cancer, Director, Familial Breast Cancer Research Unit, Women’s College Research Institute, Toronto
Dr. Narod introduced data from an ongoing study of 8,058 women from 11 countries, all known BRCA1 or BRCA2 mutation carriers, who are followed with questionnaires every two years. He discussed the risks and benefits of oral contraceptives, fertility treatment, and hormone replacement therapy for BRCA carriers. An in-depth review of this discussion will appear in next quarter’s Joining FORCEs.
Dr. Narod also shared study data regarding international variations of the decision to undergo prophylactic surgeries:
Percentage of previvors choosing prophylactic mastectomy:
According to Dr. Narod, none of the 174 women in the study who chose bilateral mastectomy developed subsequent breast cancer. Of the 1,134 women who did not choose mastectomy, 76 developed breast cancer within a four-year followup period.
Percentage of breast cancer survivors choosing contralateral prophylactic mastectomy (removal of the opposite breast):
Percentage of BRCA carriers choosing prophylactic oophorectomy:
A free webcast is available of this session on our Joining FORCEs Conference webcast page.