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Experts generally agree that bilateral salpingo-oophorectomy (removal of the fallopian tubes and ovaries) reduces breast cancer risk for BRCA mutation carriers. However, studies have shown variable degrees of reduced risk, and the precise magnitude of that benefit remains unclear. Currently, the level of reduced breast cancer risk appears to be greater for BRCA2 mutation carriers than for women with BRCA1 mutations. More research is needed to better pinpoint the precise impact risk-reducing oophorectomy on breast cancer risk reduction in BRCA mutation carriers and other high-risk women.