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Understanding BRCA & HBOC > Risk Management > Breast Cancer Chemoprevention

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Breast Cancer Chemoprevention

Learn about the steps that high-risk women can take to manage their risk and protect their health.


Chemoprevention is the use of medication to lower the risk or prevent cancer in healthy people. Some chemoprevention medications reduce breast cancer risk. However, just how well these drugs perform in high-risk women depends on each woman’s individual level of risk. Many past studies of these medications focused on women in the general population or women whose risk for breast cancer was based on the Gail Model, a risk assessment tool, therefore the research may not apply to everyone with hereditary cancer risk. When choosing the best risk management option for yourself, you need a clear sense of your risk (a health care team with expertise in managing high-risk patients can help you identify this) and an understanding of the potential benefits and side effects of chemopreventive medications.

Breast cancer risk-reducing medications within research
There are clinical trials studying medications to lower the risk for breast cancer. The following are clinical trials studying agents to lower the risk for breast cancer in high risk women:

Visit our HBOC research search tool to find additional prevention and detetion research studies. 

Updated 08/08/15

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