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Understanding BRCA & HBOC > Cancer Risk > Ovarian & Related Cancer

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Ovarian & Related Cancer

Learn about the specific risks for cancers associated with HBOC.

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Mutations in 12 genes for inherited ovarian, fallopian tube, and peritoneal carcinoma identified by massively parallel sequencing
Walsh T, Casadei S, Lee MK, et al. Proceedings of the National Academy of Sciences vol. 108, no. 44 (2011): 18032-37.

Colorectal and Other Cancer Risks for Carriers and Noncarriers From Families With a DNA Mismatch Repair Gene Mutation: A Prospective Cohort Study
Win AK, Young JP, Lindor NM, Tucker KM, Ahnen DJ, Young GP, Buchanan DD, Clendenning M, Giles GG, Winship I, Macrae FA, Goldblatt J, Southey MC, Arnold J, Thibodeau SN, Gunawardena SR, Bapat B, Baron JA, Casey G, Gallinger S, Le Marchand L, Newcomb PA, Haile RW, Hopper JL, Jenkins MA. J Clin Oncol.Vol: 30(9):958-64. March 2012

Breast and ovarian cancer risks due to inherited mutations in BRCA1 and BRCA2.
King MC, Marks JH, Mandell JB; New York Breast Cancer Study Group. King MC, Marks JH, Mandell JB; New York Breast Cancer Study Group. Science. Volume 24, p. 643-6, October 2003. (Pubmed abstract)

Primary Fallopian Tube Malignancies in BRCA-Positive Women Undergoing Surgery for Ovarian Cancer Risk Reduction
Michael J. Callahan, Christopher P. Crum, Fabiola Medeiros, David W. Kindelberger, Julia A. Elvin, Judy E. Garber, Colleen M. Feltmate, Ross S. Berkowitz, Michael G. Muto. Journal of Clinical Oncology. Volume 25, No. 25: p. 3985-3990, September 2007.

The risk of ovarian cancer after breast cancer in BRCA1 and BRCA2 carriers
Metcalfe KA, Lynch HT, Ghadirian P, Tung N, Olivotto IA, Foulkes WD, Warner E, Olopade O, Eisen A, Weber B, McLennan J, Sun P, Narod SA. Gynecologic Oncology. Volume 96, Issue 1, January 2005: p. 222-226. (Pubmed abstract)

Intra-abdominal carcinomatosis after prophylactic oophorectomy in women of hereditary breast ovarian cancer syndrome kindreds associated with BRCA1 and BRCA2 mutations
Murray Joseph Casey, Carrie Synder, Chhanda Bewtra, Steven A. Narod, Patrice Watson and Henry T. Lynch. Gynecologic Oncology. Volume 97, Issue 2 , p. 457-467, May 2005.

Average Risks of Breast and Ovarian Cancer Associated with BRCA1 or BRCA2 Mutations Detected in Case Series Unselected for Family History: A Combined Analysis of 22 Studies
A. Antoniou, P. D. P. Pharoah, S. Narod, H. A. Risch, J. E. Eyfjord, J. L. Hopper, N. Loman, H. Olsson, O. Johannsson, Å. Borg, B. Pasini, P. Radice, S. Manoukian, D. M. Eccles, N. Tang, E. Olah, H. Anton-Culver, E. Warner, J. Lubinski, J. Gronwald, B. Gorski, H. Tulinius, S. Thorlacius, H. Eerola, H. Nevanlinna, K. Syrjäkoski, O.-P. Kallioniemi, D. Thompson, C. Evans, J. Peto, F. Lalloo, D. G. Evans, and D. F. Easton. American Journal of Human Genetics. Volume 72: p. 1117-1130, May 2003.

Risk of Ovarian Cancer in BRCA1 and BRCA2 Mutation-Negative Hereditary Breast Cancer Families
Noah D. Kauff, Nandita Mitra, Mark E. Robson, Karen E. Hurley, Shaokun Chuai, Deborah Goldfrank, Eve Wadsworth, Johanna Lee, Tessa Cigler, Patrick I. Borgen, Larry Norton, Richard R. Barakat, Kenneth Offit. Journal of the National Cancer Institute. Volume 97, issue 18: p. 1382-1384, September 2005.

Fallopian Tube and Primary Peritoneal Carcinomas Associated With BRCA Mutations
Douglas A. Levine, Peter A. Argenta, Cindy J. Yee, David S. Marshall, Narciso Olvera, Faina Bogomolniy, Jamal A. Rahaman, Mark E. Robson, Kenneth Offit, Richard R. Barakat, Robert A. Soslow, Jeff Boyd. Journal of Clinical Oncology. Volume 21, Issue 22: p. 4222-4227, November 2003.

A Genetic Epidemiological Study of Carcinoma of the Fallopian Tube
Samina Aziz, Graciela Kuperstein, Barry Rosen, David Cole, Raluca Nedelcu, John McLaughlin and Steven A. Narod. Gynecologic Oncology. Volume 80, Number 341: p. 341-345, March 2001.