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Much attention has been focused on whether certain hormone preparations are safer or more effective than others. “Bio-identical” hormones are hormone preparations that are chemically identical to the hormones produced in the body—whether they originate in animals, plants, or are manufactured synthetics, they cannot be distinguished from the body’s own hormones. No evidence conclusively shows that bio-identical hormones are safer than other preparations.
Some physicians prescribe customized bio-identical compounds that are prepared by pharmacists. Compounded hormone replacement is described in more detail here.