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Genes Associated with Hereditary Cancers

Learn about genes and cancer, signs of hereditary cancer, genetic counseling, types of genetic tests and what results mean for you and your family.

Genes associated with hereditary cancer by cancer type

This table lists some of the genes associated with hereditary cancers. If you or a relative have been told that you have an inherited mutation associated with hereditary cancer, speak with a genetics expert to find out what that means for your health and health of your family. 

Type of cancer List of gene mutations

Breast cancer

 

ATM, BARD1, BRCA1, BRCA2, CDH1, CHEK2, NBN, PALB2, PTEN, RAD50, STK11, TP53 
Ovarian/fallopian tube cancer

BRCA1, BRCA2BRIP1RAD51CRAD51DEPCAM,
MLH1, MSH2, MSH6, PMS2, STK11

Pancreatic cancer

ATM, BRCA1, BRCA2, PALB2EPCAM, MLH1, MSH2, MSH6, PMS2, TP53, STK11

Prostate cancer

ATM, BRCA1, BRCA2, CHEK2, NBN

Melanoma

BRCA1, BRCA2, PTEN

Uterine cancer

EPCAMMLH1, MSH2, MSH6, PMS2, PTEN, STK11
Colon cancer CHEK2, EPCAMMLH1, MSH2, MSH6, PMS2, PTEN, STK11, TP53
Gastric cancer CDH1, STK11

 

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