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Who Should Consider Testing?

Learn about genes and cancer, signs of hereditary cancer, genetic counseling, types of genetic tests and what results mean for you and your family.

Genetic testing for people with pancreatic cancer

Although rare, pancreatic cancer can be caused by an inherited mutation in BRCA or other genes. Some experts advocate genetic testing for all pancreatic adenocarcinoma patients, as this information may be critical for other family members in terms of screening and prevention. Recent studies analyzing the number of pancreatic cancer patients who have an inherited mutation in BRCA found that:

  • up to 10% of patients with pancreatic cancer have inherited mutations in BRCA1 or BRCA2.
  • up to 17% of pancreatic cancer patients with a family history of pancreatic cancer have inherited mutations in BRCA1 or BRCA2.
  • 10-15% of pancreatic cancer patients with Ashkenazi Jewish heritage have a mutation in BRCA1 or BRCA2.  

Other gene mutations which may increase the risk for pancreatic cancer include:

Benefits of genetic testing for people with pancreatic cancer include:

updated 05/22/17

 

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