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Recent research shows a link between certain types of aggressive prostate cancers and inherited mutations in BRCA1, BRCA2, ATM and CHEK2.
Approximately 10% of men with a hormone-resistant, metastatic prostate cancer will test positive for one of these mutations. As a result, national guidelines are now beginning to recommend genetic counseling and testing for all men with metastatic prostate cancer to determine whether or not they have an inherited genetic mutation that is relevant to their cancer.
Genetic test results may provide you and your family with additional health information and help you make medical decisions. Test results may:
The following gene mutations have been linked with hereditary prostate cancer. Each gene has slightly different cancer risks and recommendations. You should speak with a genetics expert before and after genetic testing to understand which test to order and what your results mean for you and your family.
If you are a prostate cancer survivor making decisions about genetic testing, you may want additional guidance or support. FORCE's Peer Navigation Program provides expert reviewed resources and 1:1 personalized peer support by specially trained volunteers who have experienced the very challenges you face.