Research & Clinical Trials

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NCT01366144

Veliparib, Paclitaxel, and Carboplatin in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery and Liver or Kidney Dysfunction

Study identifier: NCT01366144
Full study details on clinicaltrials.gov

Name of PARP Inhibitor used in study:

Veliparib (Abbvie)

Eligibility:

  • Metastatic malignancy for which standard curative measures do not exist or are no longer effective and are likely to respond to carboplatin/paclitaxel (e.g. lung, ovarian, breast, melanoma, head and neck, endometrial, urothelial, testicular, esophageal)
  • patients who progressed on carboplatin/paclitaxel are not eligible

Type of study:

Phase I study

Treatment:

21-day cycles with veliparib orally on days 1-7 and paclitaxel and carboplatin intravenously on day 3

Study sites:

California
Duarte
City of Hope
Contact: Vincent Chung 626-471-9200 VChung@coh.org

Sacramento
UC Davis Comprehensive Cancer Center
Contact: Helen K. Chew 916-734-3772 helen.chew@ucdmc.ucdavis.edu

South Pasadena
City of Hope- South Pasadena Cancer Center
Contact: Stephen C. Koehler 626-396-2900 Skoehler@cohmg.com

Georgia
Atlanta
Emory University
Contact: Donald R. Harvey 404-778-4381

Maryland
Baltimore
Johns Hopkins University
Contact: Michael A. Carducci carducci@jhmi.edu

Massachusetts
Boston
Dana-Farber Cancer Institute
Contact: Leena Gandhi 617-632-2307

Michigan
Detroit
Wayne State University Recruiting
Patricia M. LoRusso 313-576-8716 lorussop@karmanos.org

New York
Bronx
Albert Einstein College of Medicine Recruiting
Contact: Sanjay Goel 718-904-2900 sgoel@montefiore.org

Montefiore Medical Center
Contact: Hussein A. Tawbi tawbih@upmc.edu

New York
Memorial Sloan Kettering Cancer Center
Contact: Katherine M. Bell-McGuinn 212-639-8396

Ohio
Cleveland
Case Western Reserve University
Seidman Cancer Center at University Hospitals Case Medical Center, Case Comprehensive Cancer Center Recruiting
Contact: Afshin Dowlati 216-844-3951

Pennsylvania
Hershey
Penn State Milton S Hershey Medical Center
Contact: Chandra P. Belani 717-531-1078 cbelani@psu.edu

Pittsburgh
University of Pittsburgh Cancer Institute
Contact: Hussein A. Tawbi 412-648-6466 tawbhx@upmc.edu

Wisconsin
Madison
University of Wisconsin Hospital and Clinics
Contact: Daniel L. Mulkerin 608-265-9771 dm2@medicine.wisc.edu

Page updated 06/13/13