Research Study Search Tool

Use our HBOC Research Search tool to find and participate in research focused on hereditaty cancers. Need assistance getting started?

| More

Search Results: Prevention, Detection & Risk (10 results)

Here are some research studies that may be enrolling patients like you. Please check with the study contact and your health care provider to confirm your eligibility and see if the study is right for you. Note, our search tool may not be comprehensive and additional research resources can be found here.

The Women Choosing Surgical Prevention (WISP) Trial

Prevention:
Ovarian

Quality of Life:
High Risk But No Cancer

The Women Choosing Surgical Prevention (WISP) Trial

The goal of the WISP Study is to compare whether removal of fallopian tubes only, delaying removal of the ovaries can safely improve sexual functioning and menopausal symptoms compared to standard risk-reducing removal of the ovaries and fallopian tubes (also known as risk-reducing salpingo-oophorectomy or RRSO). You can visit the WISP website for more information.

 

Metformin Hydrochloride in Patients With Atypical Hyperplasia or In Situ Breast Cancer to Placebo in Decreasing Atypical Cells in Patients With Atypical Hyperplasia or in Situ Breast Cancer

Prevention:
Breast

Metformin Hydrochloride in Patients With Atypical Hyperplasia or In Situ Breast Cancer to Placebo in Decreasing Atypical Cells in Patients With Atypical Hyperplasia or in Situ Breast Cancer

The purpose of this research study is to test whether metformin, a drug commonly used to treat diabetes, is able to get rid of atypia (early cell changes that are thought to be a marker of breast cancer risk) in women at increased risk for breast cancer. There will be testing for the presence of atypia in the breast after metformin is given to see if it can get rid of atypia. The study will compare the effects, good and/or bad, of metformin or placebo on atypia to find out which is better.

BRCA Founder Outreach Study (BFOR)

Prevention:
Breast
Ovarian
Pancreatic
Prostate

BRCA Founder Outreach Study (BFOR)

BFOR is a research study looking at ways to make genetic testing easier. It offers BRCA testing at no cost to men and women age 25 or older, who have at least one Ashkenazi Jewish grandparent. The study is open to people who live in the Boston, New York, Los Angeles or Philadelphia metropolitan areas. For more information, visit the BFOR study website

Making Genetic Testing Accessible (MAGENTA)

Prevention:
Breast
Ovarian

Making Genetic Testing Accessible (MAGENTA)

The goal of this research study is to test the effects of online genetic education alone or in combination with telephone genetic counseling in order to compare the two methods and the stress a person feels about their risk of cancer.

Researchers also want to learn how these strategies may improve your understanding of genetics, your ability to complete a quiz about genetics, and your quality of life.

For more information, visit the study website

Tampon Detection of Cancer Associated Mutations: A Pilot Study

Prevention:
Ovarian

Tampon Detection of Cancer Associated Mutations: A Pilot Study

Researchers are studying a potential method of ovarian cancer screening in high risk women to increase early detection. The study is collecting tampon samples from women with a BRCA1 mutation to look for mutations that may help detect ovarian cancer. If these mutations are found at a significant frequency, this could warrant further investigation into the use of tampons as a non-invasive screening modality for ovarian cancer. 

For more information, refer to this study flier

GENTleMEN Study: Genetic Testing for Men with Metastatic Prostate Cancer

GENTleMEN Study: Genetic Testing for Men with Metastatic Prostate Cancer

The goal of this research study is to determine if online genetic education and testing with online telephone genetic counseling is an acceptable method of delivering genetic testing to men with metastatic prostate cancer.

This study involves undergoing genetic counseling and genetic testing for inherited cancer risk.

 

Pancreatic Cancer Early Detection Program

Prevention:
Pancreatic

Pancreatic Cancer Early Detection Program

This is a study looking at esophageal ultrasound and Magnetic Resonance Imaging (MRI) as a screening for pancreatic cancer in high risk individuals. 

Dose-Response of Aerobic Training in Post-Menopausal Women at High-Risk for Development of Breast Cancer

Prevention:
Breast

Dose-Response of Aerobic Training in Post-Menopausal Women at High-Risk for Development of Breast Cancer

In this study, researchers want to determine the optimal amount of exercise needed to change certain factors associated with breast cancer risk for post-menopausal, high-risk women.

Visit the study website for more information.

The WISDOM Study: Women Informed to Screen Depending on Measures of risk

Prevention:
Breast

The WISDOM Study: Women Informed to Screen Depending on Measures of risk

The goal of the Wisdom Study is to determine if breast cancer screening can be made better by personalizing each woman’s mammogram schedule, compared to the current one-size-fits-all, annual approach. The Wisdom Study is designed to end the confusion about when to start and how often to have a mammogram. For more information, visit the WISDOM Study website

A Follow-Up Telephone Genetic Counselling Study

Prevention:
Breast
Ovarian

A Follow-Up Telephone Genetic Counselling Study

The Follow-up Telephone Genetic Counseling study lead by Dr. Kelly Metcalfe at the University of Toronto is inviting women with a BRCA1/2 mutation to participate in a clinical trial, which will provide up-to-date follow-up information on cancer risk management through a genetic counselor. For those who meet eligibility criteria, participation involves completion of two questionnaires and a scheduled session over the phone with a genetic counselor. Please contact Dawn Lee (the genetic counselor leading enrollment efforts) by email at phoneGCstudy@wchospital.ca or phone (1-416-323-6400 ext 2725) if you would like to learn more.

Additional Results on Clinicaltrials.gov: Prevention, Detection & Risk + CDH1

No Results

Clinical Trial Official Title

FORCE:Facing Our Risk of Cancer Empowered