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Research & Clinical Trials > Study Search Tool > Protocol for High-Risk Assessment, Screening, and Early Detection of Pancreatic Cancer at Moffitt Cancer Center and Lehigh Valley Hospital

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Protocol for High-Risk Assessment, Screening, and Early Detection of Pancreatic Cancer at Moffitt Cancer Center and Lehigh Valley Hospital

This study is open to:
  • Patients with 2 or more relatives with pancreatic cancer. At least one of the relatives with pancreatic cancer must be a first degree relative (mother, father, brother, sister, son, daughter). At least 40 years old or 10 years younger than the youngest age of onset of pancreatic cancer in he family
  • Peutz-Jeghers Syndrome (STK11 mutation) patients age 30 or older
  • Hereditary pancreatitis patients
  • Patients with Familial Atypical Multiple Mole Melanoma Syndrome (FAMMM)
  • Patients with BRCA2 mutation and at least one first or second degree relative with documented pancreatic cancer
This study is not open to:
  • Patients with a diagnosis of pancreatic cancer
  • Patients who are pregnant
  • Patients who do not meet the criteria listed above for being at high risk for pancreatic cancer
Protocol for High-Risk Assessment, Screening, and Early Detection of Pancreatic Cancer at Moffitt Cancer Center and Lehigh Valley Hospital

Pancreatic Cancer Early Detection at Moffitt Cancer Center and Lehigh Valley Hospital

Clinicaltrials.gov identifier:
NCT01662609

Prevention:
Pancreatic

Study Contact Information

The study is being conducted at Moffitt Cancer Center in Tampa, FL and Lehigh Valley Hospital in Allentown, PA. Contact Jason Klapman, MD: Contact by phone at: 813-745-4035 or by email.

AAbout the Study

This study's goal is to learn whether an imaging method called Endoscopic Ultrasound (EUS) can find early stage pre-cancerous or cancerous changes in the pancreas in patients at high-risk for pancreatic cancer. 

Endoscopic ultrasound is a procedure where patients are placed under anesthesia so a small tube with an imaging device at the end can be guided into the stomach in order to look for any changes or tumors in the pancreas. 

The study is open to patients who have increased risk for pancreatic cancer due to an inherited mutation and family history of cancer. 

What the Study Entails

Patients who enroll will undergo endoscopic ultrasound under anesthesia. If abnormalities are found in the pancreas, patients will be asked to undergo additional testing which may include further imaging, a fine needle aspirate, or biopsy. 

Principal Investigator

Jason Klapman, MD and Rohit Sharma, MD

Study Sites

  • Florida, Tampa: Moffitt Cancer Center
    • Contact: Natlie Burgess by phone: 813-745-4075  or email 
  • Pennsylvania, Allentown: Lehigh Valley Hospital
    •  Contact Christina Gogal by phone: 610-402-9543 or email      

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