Use our HBOC Research Search tool to find and participate in research focused on hereditaty cancers. Need assistance getting started?
This study is open to women age 25-55 who:
Women who are not eligible:
Multiple sites are enrolling throughout the US in CA, KS, NY, OH, OK, SC, TX, WI. Contact Victoria Seewaldt, MD (626) 471-7321 for more information.
The purpose of this research study is to test whether metformin, a drug commonly used to treat diabetes, is able to get rid of atypia (early cell changes that are thought to be a marker of breast cancer risk) in women at increased risk for breast cancer. There will be testing for the presence of atypia in the breast after metformin is given to see if it can get rid of atypia. The study will compare the effects, good and/or bad, of metformin or placebo on atypia to find out which is better.
This is a 2-arm, randomized, placebo-controlled, double-blind study. This study allows crossover.
Principal Investigator: Victoria Seewaldt, MD; City of Hope, Duarte, CA. (626) 471-7321