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PARP Inhibitor BRCA Breast Cancer Trials
PARP Inhibitor Breast Cancer Clinical Trials for BRCA Mutation Carriers
The below are PARP inhibitor studies currently open to breast cancer patients with a known BRCA mutation regardless of the ER/PR status of the tumor. If you have a BRCA mutation and also have triple-negative breast cancer, you may also qualify for studies enrolling triple-negative patients. Please visit our triple-negative breast cancer study page for a list of those trials. Other eligibility criteria may apply; for more details on an individual study, please contact the study coordinator or visit clinicaltrials.gov.
- NCT01074970: PARP Inhibition for Triple Negative Breast Cancer (ER-/PR-/HER2-)or BRCA1/2 Mutations
- NCT01482715: A Study of Oral Rucaparib in Patients With gBRCA Mutation Breast Cancer or Other Solid Tumor
- NCT01237067: Olaparib in Combination With Carboplatin for Refractory or Recurrent Women's Cancers
- NCT00647062: AZD2281 and Carboplatin in Treating Patients With BRCA1/BRCA2-Associated, Hereditary, or Triple Negative Metastatic or Unresectable Breast Cancer or Ovarian Epithelial Cancer
- NCT01445418: AZD2281 Plus Carboplatin to Treat Breast and Ovarian Cancer
- NCT01311713: Study to Determine the Maximum Tolerated Dose of the PARP Inhibitor CEP-9722 in Patients With Solid Tumors
- NCT00813956: A Phase 2 Study of Standard Chemotherapy Plus BSI-201 (PARP Inhibitor also known as iniparib) in the Neoadjuvant Treatment of Triple Negative Breast Cancer
- NCT01104259: Phase I Study of ABT-888 in Combination With Cisplatin and Vinorelbine for Patients With Advanced Triple Negative Breast Cancer and/or BRCA-Mutation Associated Breast Cancer
- NCT01149083: Veliparib With or Without Carboplatin in Treating Patients With Stage III or Stage IV Breast Cancer
- NCT00892736: ABT-888 in Treating Patients With Malignant Solid Tumors That Did Not Respond to Previous Therapy
- NCT01281150: Veliparib in Combination With Carboplatin and Paclitaxel in Treating Patients With Locally Advanced or Metastatic Solid Tumors
- NCT01042379: I-SPY 2 TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer
- NCT01286987: Study of BMN 673, a PARP Inhibitor, in Patients With Advanced or Recurrent Solid Tumors
Page updated 11/30/11
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