NCT01149083

Veliparib With or Without Carboplatin in Treating Patients With Stage III or Stage IV Breast Cancer

Study identifier: NCT01149083
Full study details on clinicaltrials.gov

Name of PARP Inhibitor used in study:

Veliparib (Abbott)

Eligibility:

• Histologically confirmed metastatic or locally advanced breast cancer
  • Disease not amenable to surgery
  • Standard curative measures do not exist or are no longer effective

• Patient must have a known BRCA mutation
• Measurable disease by RECIST criteria

Type of study:

Phase II randomized study

Treatment:

• Arm I: Patients receive oral veliparib twice daily on days 1-21.
• Arm II: Patients receive carboplatin IV over 30 minutes on day 1 and veliparib as in
  arm I.

Study sites:

Arizona

Mayo Clinic Scottsdale   
Scottsdale, Arizona, 85259-5499
Contact: Clinical Trials Office - All Mayo Clinic Locations     507-538-7623       

California

City of Hope Comprehensive Cancer Center
Duarte, California, 91010-3000
Contact: Clinical Trials Office - City of Hope Comprehensive Cancer Cen    
800-826-4673     becomingapatient@coh.org   

USC/Norris Comprehensive Cancer Center and Hospital
Los Angeles, California, 90089-9181
Contact: Clinical Trials Office - USC/Norris Cancer Center     323-865-0451       

University of California Davis Cancer Center
Sacramento, California, 95817
Contact: Clinical Trials Office - University of California Davis Cancer   916-734-3089    

Colorado   

University of Colorado Cancer Center at UC Health Sciences Center
Aurora, Colorado, 80045
Contact: Clinical Trials Office - University of Colorado Cancer Center 720-848-0650

Florida

Mayo Clinic - Jacksonville             
Jacksonville, Florida, 32224
Contact: Clinical Trials Office - All Mayo Clinic Locations  507-538-7623       

Illinois

University of Chicago Cancer Research Center     
Chicago, Illinois, 60637-1470
Contact: Clinical Trials Office - University of Chicago Cancer Research 773-834-7424       

Maryland

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins     
Baltimore, Maryland, 21231-2410
Contact: Clinical Trials Office - Sidney Kimmel Cancer Ce    410-955-8804     jhcccro@jhmi.edu   

Massachusetts

Beth Israel Deaconess Medical Center      Recruiting
Boston, Massachusetts, 02215
Contact: Clinical Trials Office - Beth Israel Deaconess Medical Center     617-667-9925       

Dana-Farber/Harvard Cancer Center at Dana-Farber Cancer Institute          
Boston, Massachusetts, 02115-6084
Contact: Judy Garber, MD     617-632-2282     judy_garber@dfci.harvard.edu   

Massachusetts General Hospital 
Boston, Massachusetts, 02114
Contact: Clinical Trials Office - Massachusetts General Hospital     877-726-5130       

Minnesota

Mayo Clinic Cancer Center           
Rochester, Minnesota, 55905
Contact: Clinical Trials Office - All Mayo Clinic Locations     507-538-7623       

Mayo Clinic Cancer Research Consortium
Rochester, Minnesota, 55905
Contact: Clinical Trials Office - Mayo Clinic Cancer Research Consortiu     507-538-7623       

Missouri

Siteman Cancer Center at Barnes-Jewish Hospital - Saint Louis       
Saint Louis, Missouri, 63110
Contact: Cynthia X. Ma, MD, PhD     314-362-9383       

New York

New York Cancer Consortium     
Bronx, New York, 10461
Contact: Joseph A. Sparano, MD     718-904-2555       

Memorial Sloan-Kettering Cancer Center
New York, New York, 10065
Contact: David Paul Kelsen, MD     212-639-2428       

New York Weill Cornell Cancer Center at Cornell University
New York, New York, 10021
Contact: Clinical Trials Office - New York Weill Cornell Cancer Center  212-746-1848       

Pennsylvania

Penn State Hershey Cancer Institute at Milton S. Hershey Medical Center
Hershey, Pennsylvania, 17033-0850
Contact: Clinical Trials Office - Penn State Hershey Cancer Institute a     717-531-3779     CTO@hmc.psu.edu   

UPMC Cancer Center at Magee-Womens Hospital
Pittsburgh, Pennsylvania, 15213
Contact: Clinical Trials Office - UPMC Cancer Center at Magee-Womens Ho     412-647-2811       

UPMC Cancer Centers    
Pittsburgh, Pennsylvania, 15232
Contact: Clinical Trials Office - UPMC Cancer Centers     412-647-8073       

Texas

M. D. Anderson Cancer Center at University of Texas
Houston, Texas, 77030-4009
Contact: Clinical Trials Office - M. D. Anderson Cancer Center 713-792-3245

 

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