AZD2281 and Carboplatin in Treating Patients With BRCA1/BRCA2-Associated, Hereditary, or Triple Negative Metastatic or Unresectable Breast Cancer or Ovarian Epithelial Cancer
Study identifier: NCT00647062
Full study details on clinicaltrials.gov
Name of PARP Inhibitor used in study:
- Documented deleterious BRCA1/BRCA2 germline mutation or BRCAPRO score ≥ 30%
- Sporadic ovarian serous epithelial cancer with negative family history, BRCAPRO score ≤ 20%, or negative BRCA1/BRCA2 mutation
- Metastatic or unresectable disease for which standard curative measures do not exist or are no longer effective
- Measurable and/or evaluable disease
- At least 6 months since prior platinum drugs
- Patients with platinum-resistant disease are eligible
Type of study:
Phase I study
Participants receive a combination of olaparib and carboplatin.
National Institutes of Health Clinical Center
Bethesda, Maryland, 20892
Contact: Laura D.Otten, R.N., B.S.N., O.C.N.
Medical Oncology Referral Coordinator 301-451-1228
1-866-611-6310 (Toll Free) firstname.lastname@example.org
Page updated 03/26/11
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