XRAYS Quarterly Digest

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XRAYS Quarterly Digest For Summer 2017

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A compilation of the past quarter's reviewed articles.

FORCE's eXamining the Relevance of Articles for Young Survivors (XRAYS) program, is a reliable resource designed to help young breast cancer survivors and high-risk women navigate through breast cancer research related news and information

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STUDY: Beauty and the breast: hair product use and breast cancer risk

Past studies using mostly animal models showed a link between use of hair products (dyes, straighteners and relaxers) and increased risk of certain cancers. In this study, researchers looked at data on hair product use among African-American (AA) and White women to see if certain types of hair products increased breast cancer risk, and how that risk might differ between race and breast cancer hormone status. (9/27/2017)

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ARTICLE: Can lifestyle changes impact breast cancer risk?

A recent New York Times article shared how “adopting protective living habits”  could help keep breast cancer “at bay”.  While many of these lifestyle changes and strategies like not smoking, avoiding weight gain, reducing alcohol consumption, eating a heart-healthy diet, and increasing physical activity have been shown to reduce breast cancer risk, there are other risk factors that one cannot control such as having a BRCA or other mutation that significantly increases breast cancer risk. Importantly, no one strategy has been proven to totally eliminate breast cancer risk. However many of these approaches have overall health benefits. (9/21/2017)

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STUDY: Does expanded genetic testing benefit Jewish women diagnosed with breast cancer?

Carrying a BRCA gene mutation increases the risk of cancer in both women and men. Such information is valuable for people diagnosed with cancer and can affect medical decisions for both the patient and his or her family members. Approximately 2% of people of Ashkenazi Jewish (Eastern European) descent carry one of three common BRCA gene mutations. For Ashkenazi Jewish women diagnosed with breast cancer who do not carry one of the three common BRCA mutations, little is known about their chance of carrying another hereditary mutation that may increase risk. This study looked at how often Ashkenazi Jewish women diagnosed with breast cancer were found to carry mutations other than the three common BRCA gene mutations found among individuals of Ashkenazi Jewish descent. (09/13/17)

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STUDY: Breast cancers can disappear without treatment: fact or fiction?

Previous studies and news headlines have reported that it is possible for breast cancers to regress or disappear on their own. Is this true? The authors of the current research study show that of 479 untreated breast cancers detected by screening mammography, none regressed or spontaneously disappeared on their own. (9/7/17)

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STUDY: Does aspirin lower a woman’s breast cancer risk?

Women who take aspirin regularly may have a reduced risk of breast cancer. However, previous studies have reported mixed results—some suggest risk is lowered with aspirin while others do not see a protective effect. Few of these studies have looked at whether this potential benefit of aspirin is linked to specific types of breast cancer. This study found a modest reduction in breast cancer risk for women who took a low-dose aspirin at least three times per week, but only for one subtype of breast cancer. Women who took aspirin were less likely to develop ER/PR-positive/Her2- negative breast cancer, the most common type of breast cancer. This study found no breast cancer risk reduction for women who used regular-dose aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDS). (8/29/17)

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ARTICLE: Parents face challenges when deciding the best time to tell children that they may be at high risk for cancer

When certain types of cancers run in families, genetic testing can determine whether the cause is hereditary. Genetic testing can help family members understand their cancer risk and make medical decisions to stay healthy. A test result can provide significant insight, but it also creates challenges for parents, because gene mutations that cause hereditary cancers can be passed from mothers and fathers to sons and daughters. People with these mutations must make difficult decisions about when to tell their children that they too may have inherited the mutation. (8/22/2017)

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STUDY: Breast cancer rates are rapidly increasing among Asian women in California

The majority of racial groups in the United States have seen declines in breast cancer rates. However, this study provides new insights into the patterns of breast cancer rates in Asian American subgroups in California. Using 26 years of data, this research found that breast cancer is rapidly increasing among this population, contrasting to a decline in rates among non-Hispanic white women in California and nationwide. (8/15/17)

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STUDY: Do physicians recommend breast cancer screenings based on guidelines?

Several guidelines help physicians decide when a woman should begin screening for breast cancer and how often she should be screened. However, are these guidelines put into use in the clinic? (8/8/17)

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ARTICLE: Report on vaccines to prevent hereditary cancer

On May 30th Good Morning America aired a segment entitled “Can a vaccine help prevent breast cancer at its earliest stages?” The story outlines the need for cancer prevention and hints at early research into a cancer vaccine. (8/1/17)

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STUDY: New cancer risk estimates for BRCA1/2 mutation carriers

Cancer risk estimates for BRCA1 and BRCA2 mutation carriers are important because they impact patient decision-making. Until now, almost all risk estimates for mutation carriers were based on results of retrospective studies that looked back on mutation carriers who had cancer. This new study is prospective—it followed almost 10,000 BRCA mutation carriers without cancer to see if or when they developed breast or ovarian cancer. The cancer risk estimates of this study may be more accurate because it followed mutation carriers who did not have cancer over time. (7/28/17)

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ARTICLE: Can your breast cancer come back?

Elaine Howley’s piece for US News & World Report, “Can My Breast Cancer Come Back?” examines a common misperception that many breast cancer patients have after completing treatment, and explains what can actually occur. (7/25/17)

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STUDY: Gaps in genetic testing and decision-making for women with early-stage breast cancer

Genetic testing for cancer risk is now more affordable and easier to obtain. As a result, many breast cancer patients are tested without ever seeing a genetic counselor. Genetic testing results affect treatment decision making, but they can be confusing, especially if patients do not receive genetic counseling. This study looks at breast cancer patients’ experiences following genetic testing and how testing results affect surgical decision making. (7/14/17)

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STUDY: Immunotherapy shows promise in triple-negative breast cancer

Patients diagnosed with triple-negative breast cancer (TNBC) do not have many treatment options. Immunotherapy, a new type of cancer treatment, pushes the body’s natural defense or immune system to fight cancer. A new immunotherapy drug, atezolizumab (Tecentriq) may improve survival for patients with metastatic TNBC. (07/11/17)

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STUDY: Diet during teen years and early adulthood is linked to breast cancer risk

During teen years, breast tissue grows rapidly in young girls and is more likely to be harmed by substances that are known to cause cancer. Few studies have looked at the relationship between diet during puberty and breast cancer risk. This study looks at how a woman’s diet during their teenage years and early adulthood is associated with breast cancer development later in life. (6/30/17)

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